STRATEGIES TO GENETICALLY MODULATE DENDRITIC CELLS TO POTENTIATE ANTI-TUMOR RESPONSES IN HEMATOLOGIC MALIGNANCIES

Strategies to Genetically Modulate Dendritic Cells to Potentiate Anti-Tumor Responses in Hematologic Malignancies

Dendritic cell (DC) vaccination has been investigated as a potential strategy to target hematologic malignancies, while generating sustained immunological responses to control potential future relapse.Nonetheless, few clinical trials have shown robust long-term efficacy.It has been suggested that a combination of surmountable shortcomings, such as

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Efficacy and Safety of Insulin Glargine 300 U/mL versus 100 U/mL in Diabetes Mellitus: A Comprehensive Review of the Literature

To achieve good metabolic control in diabetes and maintain it in the long term, a combination of changes in lifestyle and pharmacological treatment is necessary.The need for insulin depends upon the balance between Gout Formula insulin secretion and insulin resistance.Insulin is considered the most effective glucose-lowering therapy available and i

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Microstructural and Mechanical Property Analyses of Ti/Al/Ti Laminated Composites Prepared by Ultrasonic Welding

Ti/Al/Ti laminated composite material is an ideal material for high-temperature parts and protective armor in the aerospace field because of its high specific strength and high temperature oxidation resistance.To improve the joint strength, the ultrasonic welding solid-phase joining technology is used to prepare Ti/Al/Ti laminated composites.The re

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Interplay of inert doublet and vector-like lepton triplet with displaced vertices at the LHC/FCC and MATHUSLA

Abstract We study the interaction between the inert Higgs doublet (IDM) dark matter and a vector-like SU(2) triplet lepton (VLL), both of which are Z 2-odd.The vector current of the VLL with the Z-boson rules out a fermionic or two-component dark matter scenario.However, a compressed mass spectrum and a sufficiently small Yukawa coupling allows co-

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